SMALLDOSE 0 F 2 - DEOXY - I ] } - GLUCOSE CeMPLETELY EXICLUDES THE OVERGROWTH OF FIBROBLASTS
نویسنده
چکیده
Synopsis The present werlc has been undertaken to assess the effects of a small dose of 2-deoxy-D-glucose on proliferation of fibrob]asts in culture by morphological criteria. Fibroblasts in culture medium with 2-deoxy-D-glucose proliferated only to a slight clegree, but eell confluence was not achieved, They became swollen and the cytoplasm was increasingly occupied by lucent area. These changesbeeame prominent on the 10th day cf incubation. When cell mixtures of fibroblasts and TYK-nu <cell line of undifferentiated adenocarcinoma ef the ovary) or TYK-nu only were incubated under the infiuenee of 2-deoxy-D-glucose, the
منابع مشابه
Inhibition of gold thioglucose-induced hypothalamic obesity by glucose analogues.
LIKUSKI, HENRY J., ALBERT F. DEBONS, AND ROGER J. CLOUTIER. Inhibition of go Id thioghcose-induced hypothalamic obesity by glucose analogues. Am. J. Physiol. 2 12(3) 669-676. 1967.--Female CBA mice were used to determine the effect of the glucose inhibitors, 2-deoxy-n-glucose and 2-amino-2-deoxy-oglucose on gold thioglucose-induced hypothalamic obesity. A marked inhibition in the incidence of o...
متن کاملInhibition of gold thioglucose-induced hypothalamic obesity by glucose analogued
LIKUSKI, HENRY J., ALBERT F. DEBONS, AND ROGER J. CLOUTIER. Inhibition of go Id thioghcose-induced hypothalamic obesity by glucose analogues. Am. J. Physiol. 2 12(3) 669-676. 1967.--Female CBA mice were used to determine the effect of the glucose inhibitors, 2-deoxy-n-glucose and 2-amino-2-deoxy-oglucose on gold thioglucose-induced hypothalamic obesity. A marked inhibition in the incidence of o...
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